, also known as xylocaine
, is a medication used to numb tissue in a specific area
(local anesthetic). It is also used to treat ventricular tachycardia
and to perform nerve blocks
. Lidocaine mixed with a small amount of adrenaline
(epinephrine) is available to allow larger doses for numbing, to decrease bleeding, and to make the numbing effect last longer. When used as an injectable, it typically begins working within four minutes and lasts for half an hour to three hours. Lidocaine mixtures may also be applied directly to the skin or mucous membranes
to numb the area.
Common side effects with intravenous use include sleepiness, muscle twitching, confusion, changes in vision, numbness, tingling, and vomiting. It can cause low blood pressure
and an irregular heart rate. There are concerns that injecting it into a joint can cause problems with the cartilage
. It appears to be generally safe for use in pregnancy
. A lower dose may be required in those with liver problems. It is generally safe to use in those allergic to tetracaine
. Lidocaine is an antiarrhythmic medication
of the class Ib type. This means it works by blocking sodium channels
and thus decreasing the rate of contractions of the heart. When it is used locally as a numbing agent, local neurons cannot signal the brain
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